Lecture Presentations  
Third Year, Pathobiochemistry, Winter Term, 2011/2012

These presentations have been provided by our lecturers during the academic years 2009/10 and 2010/2011, and may be modified and updated during the current academic year.
Introduction to biochemical genetics MUDr. Martin Hřebíček
Prof. MUDr. Viktor Kožich, CSc.
Hereditary disorders of metabolism
and biogenesis of lysosomes

Peroxisomal disorders
MUDr. Martin Hřebíček
Disorders of purine and pyrimidine metabolism
and porphyrias
Prof. MUDr. Viktor Kožich, CSc
Hereditary disorders of amino acid metabolism Prof. MUDr. Viktor Kožich, CSc.
Hereditary disorders of saccharide metabolism
and disorders of N-glycan synthesis
MUDr. Martin Hřebíček
Disorders of mitochondrial metabolism MUDr. Martin Hřebíček
Diagnostics of monogenic disorders of metabolism
Therapy of monogenic disorders of metabolism
Prof. MUDr. Viktor Kožich, CSc.
Mechanisms of tumour disease formation
(Physical, chemical and viral carcinogenesis)
Doc. MUDr. Jaromír Křemen, CSc.
Pathobiochemistry of tumorigenesis (pathobiochemistry of malignant transformation) Doc. MUDr. Zdeněk Kleibl, PhD.
Principles of cancer progression
(regulation of angiogenesis, formation of metastases)
MUDr. Michal Zikán, PhD.
Signal transduction elements
as therapeutic targets
Prof. MUDr. Aleksi Šedo, DrSc.
DNA-based diagnostics in oncology Doc. MUDr. Petr Pohlreich, CSc.
Biochemical principles of anticancer treatment: Chemotherapy and immunotherapy MUDr. Martin Matějů
Hormonal therapy, targeted therapy,
tumour markers
MUDr. Martin Matějů
Disorders of acid-base balance MUDr. Martin Vejražka, PhD.
Reactive oxygen species in the body.
The antioxidant defence
MUDr. Jan Pláteník, PhD.
Ageing MUDr. Jan Pláteník, PhD.
Atherosclerosis MUDr. Martin Vejražka, PhD.
Disorders of protein folding and
their clinical consequences. Prions
Prof. MUDr. Jiří Jonák, DrSc.
Non-enzymatic glycations, insulinoresistance, metabolic syndrome MUDr. Jan Krtil
Death of Heart & Neuronal Cell: Ischemia/Reperfusion Injury
MUDr. Jan Pláteník, PhD.
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